RESULTS: 4 of 5 patients had complete response after 5 weekly cycles (Koukourakis et al, 2010 Int J Radiation Oncology Biol Phys 78, 150-155).
Regulon, Inc (Regulon) is a biopharmaceutical company committed to the discovery, development, testing, and commercialization of low toxicity anti-cancer pharmaceuticals based on a unique patented encapsulation technology. The company was founded in 1997 in Silicon Valley, California (USA) and is based in Athens, Greece & with operations in Europe and Asia. Our objective is to develop a broad range of drugs to be used in cancer therapy. We believe we have achieved a breakthrough in the development of a unique liposome encapsulation technology. Regulon engages in the discovery and development of nanopharmaceutics in oncology based on liposome encapsulation platform technology. Its products include Lipoplatin, a liposomally encapsulated cisplatin for various cancer indications, including non-small cell lung cancer and pancreatic cancer. Regulon's unique liposome encapsulation technology applicable to drugs, small molecules, peptides, proteins and viruses, significantly reduces the side effects of chemotherapy known to exacerbate the quality of life (QOL) of cancer patients. The firm has successfully applied this technology to encapsulate two members of the platinum family of anticancer drugs: cisplatin and oxaliplatin.
Lipoplatin brought a revolution in classical chemotherapy because it does not affect healthy tissue after intravenous administration, concentrating in tumor tissue and metastases.
High Standards - Patients are treated in the best clinics of Greece that meet the highest international and European standards on the basis of its own developments and technologies agreed and approved by the EMA (European Medical Association) and the Ministry of Health of Greece.
Clinical researches - They showed extremely low toxicity with an improved therapeutic effect (index).
Results of treatment - The drug developed by the company has anti-cancer efficacy more than 10-50 times higher than "traditional" drugs and treatment methods.